Glycon MR Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Warnings Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Thai FDA Category Presentation/Packing

Concise Prescribing Info

Contents

Gliclazide

Indications/Uses

Adults w/ type 2 NIDDM when dietary measures, physical exercise & wt loss alone are insufficient to control blood glucose.

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Dosage/Direction for Use

Adult Initially 30 mg daily. Titration: Adjust dose in increments of 30 mg at least 1-mth interval & may be increased after 2 wk in patients who have not responded. Max: 120 mg once daily.

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Overdosage

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Administration

Should be taken with food: Take w/ breakfast. Tab may be divided into equal doses, do not crush/chew.

Contraindications

Known hypersensitivity to gliclazide or other sulfonylurea or sulfonamides. Type 1 DM; diabetic ketoacidosis (w/ or w/o coma); severe infection & accident. Severe renal or hepatic insufficiency. Treatment w/ miconazole. Lactation.

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Warnings

For additional cautionary notes to warn of the potential risk of using the medicine... Click to view Glycon MR detailed prescribing information

Special Precautions

Discontinue use if skin rash, blisters, detachment of skin & epithelial lining in oral cavity, throat, nose, genital organ & conjunctivitis occurs. Hypoglycemic symptoms eg, hunger, palpitation, sweating. Malnourished patients. Patients w/ G6PD deficiency. May elevate liver enzymes. Avoid alcohol intake during treatment. Renal impairment. Hepatic function, adrenal &/or pituitary insufficiency. Avoid during pregnancy & lactation. Elderly or debilitated patients.

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Use In Pregnancy & Lactation

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Adverse Reactions

Hypoglycemia. Angina pectoris, HTN, peripheral edema; depression, dizziness, headache, insomnia, neuralgia; dermatitis, dermatological disease, pruritus, rash, (includes maculopapular & morbilliform rash); hyperglycemia, hyperlipidemia, increased lactate dehydrogenase, lipid metabolism disorder; abdominal pain, constipation, diarrhea, gastritis, gastroenteritis, nausea; UTI; viral infection; arthralgia, arthritis, arthropathy, back pain, myalgia, tendonitis, weakness; conjunctivitis; otitis media; increased serum creatinine; bronchitis, cough, pharyngitis, pneumonia, rhinitis, sinusitis, URTI. DRESS, SJS, TEN.

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Drug Interactions

Prolonged hypoglycemia & disulfiram-like reactions w/ ethanol. Increased risk of phototoxic skin reactions w/ aminolevulinic acid. Inhibited metabolism w/ chloramphenicol. Enhanced hypoglycaemic effects w/ sulfonamides. Rarely, concomitant use w/ fluoroquinolones (ie, ciprofloxacin, levofloxacin, gatifloxacin). Increased effects w/ azole antifungals (ie, fluconazole, miconazole, ketoconazole, voriconazole) & cimetidine. Reduced glucose-lowering effects w/ rifampin.

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Storage

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Description

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Action

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MIMS Class

Antidiabetic Agents

ATC Classification

A10BB09 - gliclazide ; Belongs to the class of sulfonylureas. Used in the treatment of diabetes.

Thai FDA Category

Presentation/Packing

Form

Glycon MR tab 60 mg

Packing/Price

3 × 10's

Glycon MR

gliclazide

Manufacturer:

Siam Bheasach

Distributor:

Siam Pharmaceutical

Marketer:

Siam Pharmaceutical